Training the future Scientific Entrepreneurs
TCABS-E is proud to announce the postgraduate project/thesis students that successfully completed their work at TCABS-E, Visakhapatnam!
NOTE: If you are a P.G. student and are interested in working on your masters project/thesis at TCABS-E, please contact us today to reserve your spot in the lab! Email: tcabse.india@gmail.com (or) +91-8660301662.
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Alphabetically listed: (2020-2022 batch)
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Akhila: M.Sc. Biotechnology, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Isolation and amplification of MT1JP breast cancer lncRNA for cloning purposes
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Anandkumar: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Expression analysis of polyethylene terephthalate hydrolase using bacterial expression system
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Charitha: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Qualitative/quantitative estimation of glycoproteins using SDS-PAGE to determine human O-Gluc-Nac- Transferase activity
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Charithasri: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhumita & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Gene amplification of glyceraldehyde 3-phosphate dehydrogenase gene as a positive control for cancer genomics
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Harshitha: M. Sc. Human Genetics, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Genotoxic effects of insecticides on bacterial gene expression: a model study to understand similar effects in humans
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Jahnavi: M. Sc. Biochemistry, Andhra University. (Mentor: Ms. Santhinissi & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Spin column-based purification of the 18S rRNA PCR product and qualitative analysis using agarose gel electrophoresis
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Kishan: M. Sc. Biochemistry, Andhra University. (Mentor: Ms. Niharikha & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Evaluation of genotoxicity caused by the carcinogenic benzo[a]pyrene, a common ingredient of Indian tobacco chew
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Layola: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Santhinissi & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Qualitative estimation of sugar-based metabolites produced by the Lactobacillus spp.: Applications in human vaginal microbiome investigation
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Likhitha: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Santhinissi & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Qualitative estimation of peptide-based metabolites produced by the Lactobacilli spp.: Applications in human vaginal microbiome investigation
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Madhu: M. Sc. Human Genetics, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: PCR-based multiplex-site directed mutagenesis of PTEN gene to generate a double mutant for downstream skin cancer (melanoma) studies
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Manasa: M. Sc. Biochemistry, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Design of an in vitro chromogen-based biochemical enzyme assay to evaluate the potency of reversible inhibitors
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Manisha: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Novel Biophysical and Biological strategies for therapeutic miRNA delivery for Cancer and Infectious diseases
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Mustafa: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Modification of the phosphorylation sites on human HMGA1 enhancer to improve the expression of insulin receptor
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Nageswari: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Testing the expression levels of Human Sex Hormone Binding Globulin cloned under the control of an IPTG inducible promoter
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Naveenkumar: M. Sc. Human Genetics, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: PCR-based site directed mutagenesis of human BRCA1 zinc finger domain
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Niharikha: M. Sc. Biotechnology, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: In vitro assay to evaluate the metabolism of drugs and pharmaceuticals using liver extracted cytochrome P450 enzymes
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Nikhil: M. Sc. Microbiology, TSR-TBK College, Visakhapatnam (Affl.: Andhra University). (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Heat-shock transformation of E. coli cells with pUC19 plasmid containing ampicillin-resistance
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Pavan: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Estimation of Human Glutathione-S-transferase enzyme expression in bacterial cells
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Pradeepa: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: PCR-Site directed Mutagenesis of Human K-RAS Gene to generate the Q61H mutant
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Ramani: M. Sc. Biotechnology, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: PCR-based site directed mutagenesis of JAK-1 to generate the V658F mutant that is involved in acute lymphoid leukemia
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Rasheeda: M. Sc. Human Genetics, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Guide-RNA design for CRISPR-based detection of cystic fibrosis
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Ratnam: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Biochemical evaluation of reversible inhibitors against the collagenase type1, matrix metalloproteinase
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SaisriTej: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: Evaluating the enzymatic activity of polyethylene terephthalate hydrolase fusion protein
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Saivikas: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: cDNA synthesis and amplification protocol for cloning mitochondrial proteins
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Sravani: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhumita & Supervisor: Dr. Ravikiran S. Yedidi)
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Title: PCR-based gene amplification of the 18s rRNA gene as a positive control for cancer genomics
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Alphabetically listed: (2019-2021 batch)
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Aishwarya: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)
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Title: RNA extraction and gene expression analysis in HepG2 cells using quantitative PCR.
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Amulya: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)
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Title: Structural insights into the regulation of human thyroglobulin protein.
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Anilkumar: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)
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Title: Molecular modeling of the clinically found C16G mutation in the human breast cancer protein, BRCA1.
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Apparao: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)
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Title: Active site analysis of human O-Glc-Nac-transferase with a focus to design inhibitors for diabetes type-2.
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Beulah: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)
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Title: Molecular manipulation of SHBG gene expression as a potential therapeutic approach for polycystic ovarian syndrome.
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Bindu: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Estimation of human error in biological laboratory based experimental data using statistical analysis.
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Harsha: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Importance of master-mix preparation in Polymerase Chain Reaction to reduce the human error.
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Jahnavi: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Qualitative analysis of proteins using SDS-PAGE.
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Jessica: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)
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Title: Cloning the microRNA-25 into an expression vector for synthetic biology applications.
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Jyothi: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Effect of incubation temperature on the activity of MBRE001-EcoRI endonuclease in T4-lambda DNA restriction digestion.
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Kajal: M.Sc. Microbiology, GITAM University, Visakhapatnam.
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Title: Targeting multiple genomic sites of HIV-1 clade-C with specific primers towards CRISPR/Cas9-based HIV diagnosis.
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Kusukumar: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)
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Title: PCR-genotyping the white spot syndrome virus in aquaculture ponds.
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Lalitha: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)
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Title: Identification of caspase cleavage sites on human thyroglobulin protein towards controlling hyperthyroidism.
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Lokesh: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Effect of incubation temperature on the MBRE003-HindIII endonuclease activity in T4-lambda DNA restriction digestion.
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Madhavarao: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)
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Title: Is human O-Gluc-Nac-transferase (hOGT) an ideal target to design inhibitors for diabetes type-2?.
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Manasa: M.Sc. Human Genetics, Andhra University, Visakhapatnam.
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Title: Screening the MiR-25 database revealed Rab23 protein as one of its onco-targets for potential therapeutic design.
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Mary: M.Sc. Applied Microbiology, Sri Padmavati Mahila Visva Vidyalayam, Tirupathi.
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Title: In silico evaluation of chymosin active site for targeted enzyme evolution towards bacterial strain development in cheese industry.
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Mounika, P.: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Transformation of MBT111-DH5-alpha competent E. coli cells with pUC19 plasmid using heat-shock method.
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Mounika, S.: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Evaluation of transformation efficiency in MBT111-DH5-alpha competent E. coli cells with pUC19 plasmid.
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Nani: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Preparation of chemically competent TKC027 E.coli cells for transformation with pUC19 plasmid.
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Naveen, K.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Significance of buffer ionic strength in voltage maintenance during agarose gel electrophoresis.
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Naveen, M.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Estimation of protein purity qualitatively using SDS-PAGE during protein purification as a part of quality control.
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Pavitra: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Homology modeling of human thyroid peroxidase to understand its structural features towards drug design for hypothyroidism.
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Prameela: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Inactivation of T4-DNA ligase enzyme activity by increase in the incubation temperature during ligation.
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Rajkumar: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)
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Title: Cloning the C-terminal domain of HIV-gp120 into an expression vector.
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Rajyalakshmi: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)
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Title: PCR-amplification of PTEN-cdRNA for cloning into an expression vector.
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Ramya, B.: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Screening for transformants of DH5-alpha E. coli cells using X-gal/IPTG system for blue colonies
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Ramya, P.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Dependence of complete DNA digestion by HindIII endonuclease on the length of reaction incubation time.
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Sandhya: M.Sc. Microbiology, GITAM University, Visakhapatnam.
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Title: Screening the MiR-25 database revealed FBXW7 protein as one of its onco-targets for potential therapeutic design.
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Satish, T.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Effect of the ligation reaction incubation time on the efficiency of TKC193-T4-DNA ligase catalytic activity.
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Satish, T.V.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Dependence of EcoRI endonuclease on the length of reaction incubation time for complete DNA digestion.
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Sindhusha: M.Sc. Biochemistry, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)
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Title: Inhibition of androgen producing enzymes as a possible therapeutic approach to control polycystic ovarian syndrome.
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Sirisha: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University).
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Title: Plasmid DNA extraction from overnight E. coli minicultures using the miniprep methodology.
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Subhashini: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)
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Title: Is human thyroid peroxidase enzyme the right target towards drug design in hypothyroidism?
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Sunanda: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)
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Title: Evaluation of TKC120-Taq DNA polymerase catalytic activity in polymerase chain reaction.
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Suraj: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)
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Title: Structural insights into sphingosine kinase-1 as a drug target in highly metastatic triple-negative breast cancer.
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Suresh: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Molecular modeling and analysis of mutant p53-DNA-binding domain to design inhibitors for the treatment of glioblastoma.
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Sushmitha: M.Sc. Applied Microbiology, Sri Padmavati Mahila Visva Vidyalayam, Tirupathi.
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Title: In silico evaluation of Pepsinogen active site for targeted enzyme evolution towards bacterial strain development in cheese production.
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Tanuja: M.Sc. Biotechnology, Reva University, Bangalore.
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Title: HIV antibody engineering.
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​Urmila: M.Sc. Human Genetics, Andhra University, Visakhapatnam.​
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Title: Screening the MiR-25 database revealed KLF4 protein as one of its onco-targets for potential therapeutic design.
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Vanitha: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Re-designing the HIV-1 Antibodies to optimize their therapeutic capabilities towards passive immunization.
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Venkatalakshmi: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Structural insights into cathepsin cleavage sites mapped on the human thyroglobulin protein for therapeutic implications in hyperthyroidism.
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Venkatesh: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Structural insights into the human p53 protein as a potential therapeutic target for glioblastoma.
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Vidyasri: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University).
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Title: Qualitative and quantitative analysis of plasmid DNA miniprep samples.
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​Vijaya: M.Sc. Microbiology, GITAM University, Visakhapatnam.​
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Title: Designing specific primers targeting multiple genomic sites of HIV-1 clade-B towards CRISPR/Cas9-based HIV diagnosis.
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Vijaykumar: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Pros and cons of targeting the human p53 mutants therapeutically for the treatment of glioblastoma.
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Vinaykumar: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Structural insights into the HMGA1 transcription factor for therapeutic intervention in type-2 diabetes.
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Vyshnavi: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).
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Title: Structural insights into the gp120 protein of HIV-1 mutant strains compared to the wild type strain for antibody design.
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​Yamini: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University).
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Title: Dependence of the final product concentration on the number of cycles in polymerase chain reaction.
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Yogita: M.Sc. Biochemistry, Sri Padmavati Mahila Visva Vidyalayam, Tirupathi.
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Title: Structural analysis of K-Ras G12V/D mutants that are clinically seen in cervical cancer patients for drug discovery opportunities.
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