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TCABS-E is proud to announce the postgraduate project/thesis students that successfully completed their work at TCABS-E, Visakhapatnam!

NOTE: If you are a P.G. student and are interested in working on your masters project/thesis at TCABS-E, please contact us today to reserve your spot in the lab! Email: tcabse.india@gmail.com (or) +91-8660301662.

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Alphabetically listed: (2020-2022 batch)

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  • Akhila: M.Sc. Biotechnology, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Isolation and amplification of MT1JP breast cancer lncRNA for cloning purposes

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  • Anandkumar: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Expression analysis of polyethylene terephthalate hydrolase using bacterial expression system

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  • Charitha: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Qualitative/quantitative estimation of glycoproteins using SDS-PAGE to determine human O-Gluc-Nac- Transferase activity

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  • Charithasri: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhumita & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Gene amplification of glyceraldehyde 3-phosphate dehydrogenase gene as a positive control for cancer genomics

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  • Harshitha: M. Sc. Human Genetics, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Genotoxic effects of insecticides on bacterial gene expression: a model study to understand similar effects in humans

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  • Jahnavi: M. Sc. Biochemistry, Andhra University. (Mentor: Ms. Santhinissi & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Spin column-based purification of the 18S rRNA PCR product and qualitative analysis using agarose gel electrophoresis

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  • Kishan: M. Sc. Biochemistry, Andhra University. (Mentor: Ms. Niharikha & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Evaluation of genotoxicity caused by the carcinogenic benzo[a]pyrene, a common ingredient of Indian tobacco chew

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  • Layola: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Santhinissi & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Qualitative estimation of sugar-based metabolites produced by the Lactobacillus spp.: Applications in human vaginal microbiome investigation

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  • Likhitha: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Santhinissi & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Qualitative estimation of peptide-based metabolites produced by the Lactobacilli spp.: Applications in human vaginal microbiome investigation

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  • Madhu: M. Sc. Human Genetics, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: PCR-based multiplex-site directed mutagenesis of PTEN gene to generate a double mutant for downstream skin cancer (melanoma) studies

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  • Manasa: M. Sc. Biochemistry, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Design of an in vitro chromogen-based biochemical enzyme assay to evaluate the potency of reversible inhibitors

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  • Manisha: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Novel Biophysical and Biological strategies for therapeutic miRNA delivery for Cancer and Infectious diseases

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  • Mustafa: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Modification of the phosphorylation sites on human HMGA1 enhancer to improve the expression of insulin receptor

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  • Nageswari: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Testing the expression levels of Human Sex Hormone Binding Globulin cloned under the control of an IPTG inducible promoter

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  • Naveenkumar: M. Sc. Human Genetics, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: PCR-based site directed mutagenesis of human BRCA1 zinc finger domain

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  • Niharikha: M. Sc. Biotechnology, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: In vitro assay to evaluate the metabolism of drugs and pharmaceuticals using liver extracted cytochrome P450 enzymes

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  • Nikhil: M. Sc. Microbiology, TSR-TBK College, Visakhapatnam (Affl.: Andhra University). (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Heat-shock transformation of E. coli cells with pUC19 plasmid containing ampicillin-resistance

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  • Pavan: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Estimation of Human Glutathione-S-transferase enzyme expression in bacterial cells

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  • Pradeepa: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: PCR-Site directed Mutagenesis of Human K-RAS Gene to generate the Q61H mutant

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  • Ramani: M. Sc. Biotechnology, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: PCR-based site directed mutagenesis of JAK-1 to generate the V658F mutant that is involved in acute lymphoid leukemia

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  • Rasheeda: M. Sc. Human Genetics, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Guide-RNA design for CRISPR-based detection of cystic fibrosis

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  • Ratnam: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Biochemical evaluation of reversible inhibitors against the collagenase type1, matrix metalloproteinase

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  • SaisriTej: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhuri & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: Evaluating the enzymatic activity of polyethylene terephthalate hydrolase fusion protein

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  • Saivikas: M. Sc. Biochemistry, Andhra University. (Mentor & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: cDNA synthesis and amplification  protocol for cloning mitochondrial proteins

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  • Sravani: M. Sc. Biotechnology, Andhra University. (Mentor: Ms. Madhumita & Supervisor: Dr. Ravikiran S. Yedidi)

    • Title: PCR-based gene amplification of the 18s rRNA gene as a positive control for cancer genomics

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Alphabetically listed: (2019-2021 batch)

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  • Aishwarya: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)

    • Title: RNA extraction and gene expression analysis in HepG2 cells using quantitative PCR.

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  • Amulya: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)

    • Title: Structural insights into the regulation of human thyroglobulin protein.

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  • Anilkumar: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)

    • Title: Molecular modeling of the clinically found C16G mutation in the human breast cancer protein, BRCA1.

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  • Apparao: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)

    • Title: Active site analysis of human O-Glc-Nac-transferase with a focus to design inhibitors for diabetes type-2.

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  • Beulah: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)

    • Title: Molecular manipulation of SHBG gene expression as a potential therapeutic approach for polycystic ovarian syndrome.

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  • Bindu: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Estimation of human error in biological laboratory based experimental data using statistical analysis.

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  • Harsha: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Importance of master-mix preparation in Polymerase Chain Reaction to reduce the human error.

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  • Jahnavi: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Qualitative analysis of proteins using SDS-PAGE.

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  • Jessica: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)

    • Title: Cloning the microRNA-25 into an expression vector for synthetic biology applications.

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  • Jyothi: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Effect of incubation temperature on the activity of MBRE001-EcoRI endonuclease in T4-lambda DNA restriction digestion.

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  • Kajal: M.Sc. Microbiology, GITAM University, Visakhapatnam.

    • Title: Targeting multiple genomic sites of HIV-1 clade-C with specific primers towards CRISPR/Cas9-based HIV diagnosis.

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  • Kusukumar: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)

    • Title: PCR-genotyping the white spot syndrome virus in aquaculture ponds.

 

  • Lalitha: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)

    • Title: Identification of caspase cleavage sites on human thyroglobulin protein towards controlling hyperthyroidism.

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  • Lokesh: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Effect of incubation temperature on the MBRE003-HindIII endonuclease activity in T4-lambda DNA restriction digestion.

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  • Madhavarao: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)

    • Title: Is human O-Gluc-Nac-transferase (hOGT) an ideal target to design inhibitors for diabetes type-2?.

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  • Manasa: M.Sc. Human Genetics, Andhra University, Visakhapatnam.

    • Title: Screening the MiR-25 database revealed Rab23 protein as one of its onco-targets for potential therapeutic design.

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  • Mary: M.Sc. Applied Microbiology, Sri Padmavati Mahila Visva Vidyalayam, Tirupathi.

    • Title: In silico evaluation of chymosin active site for targeted enzyme evolution towards bacterial strain development in cheese industry.

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  • Mounika, P.: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Transformation of MBT111-DH5-alpha competent E. coli cells with pUC19 plasmid using heat-shock method.

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  • Mounika, S.: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Evaluation of transformation efficiency in MBT111-DH5-alpha competent E. coli cells with pUC19 plasmid.

 

  • Nani: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Preparation of chemically competent TKC027 E.coli cells for transformation with pUC19 plasmid.

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  • Naveen, K.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Significance of buffer ionic strength in voltage maintenance during agarose gel electrophoresis.

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  • Naveen, M.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Estimation of protein purity qualitatively using SDS-PAGE during protein purification as a part of quality control.

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  • Pavitra: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Homology modeling of human thyroid peroxidase to understand its structural features towards drug design for hypothyroidism.

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  • Prameela: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Inactivation of T4-DNA ligase enzyme activity by increase in the incubation temperature during ligation.

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  • Rajkumar: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)

    • Title: Cloning the C-terminal domain of HIV-gp120 into an expression vector.

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  • Rajyalakshmi: M.Sc. Biotechnology, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)

    • Title: PCR-amplification of PTEN-cdRNA for cloning into an expression vector.

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  • Ramya, B.: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Screening for transformants of DH5-alpha E. coli cells using X-gal/IPTG system for blue colonies

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  • Ramya, P.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Dependence of complete DNA digestion by HindIII endonuclease on the length of reaction incubation time.

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  • Sandhya: M.Sc. Microbiology, GITAM University, Visakhapatnam.

    • Title: Screening the MiR-25 database revealed FBXW7 protein as one of its onco-targets for potential therapeutic design.

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  • Satish, T.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Effect of the ligation reaction incubation time on the efficiency of TKC193-T4-DNA ligase catalytic activity.

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  • Satish, T.V.: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Dependence of EcoRI endonuclease on the length of reaction incubation time for complete DNA digestion.

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  • Sindhusha: M.Sc. Biochemistry, Dr. Lankapalli Bullayya College, Visakhapatnam (Affl.: Andhra University)

    • Title: Inhibition of androgen producing enzymes as a possible therapeutic approach to control polycystic ovarian syndrome.

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  • Sirisha: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University).

    • Title: Plasmid DNA extraction from overnight E. coli minicultures using the miniprep methodology.

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  • Subhashini: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)

    • Title: Is human thyroid peroxidase enzyme the right target towards drug design in hypothyroidism?

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  • Sunanda: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University)

    • Title: Evaluation of TKC120-Taq DNA polymerase catalytic activity in polymerase chain reaction.

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  • Suraj: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University)

    • Title: Structural insights into sphingosine kinase-1 as a drug target in highly metastatic triple-negative breast cancer.

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  • Suresh: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Molecular modeling and analysis of mutant p53-DNA-binding domain to design inhibitors for the treatment of glioblastoma.

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  • Sushmitha: M.Sc. Applied Microbiology, Sri Padmavati Mahila Visva Vidyalayam, Tirupathi.

    • Title: In silico evaluation of Pepsinogen active site for targeted enzyme evolution towards bacterial strain development in cheese production.

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  • Tanuja: M.Sc. Biotechnology, Reva University, Bangalore.

    • Title: HIV antibody engineering.

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  • ​Urmila: M.Sc. Human Genetics, Andhra University, Visakhapatnam.​

    • Title: Screening the MiR-25 database revealed KLF4 protein as one of its onco-targets for potential therapeutic design.

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  • Vanitha: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Re-designing the HIV-1 Antibodies to optimize their therapeutic capabilities towards passive immunization.

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  • Venkatalakshmi: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Structural insights into cathepsin cleavage sites mapped on the human thyroglobulin protein for therapeutic implications in hyperthyroidism.

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  • Venkatesh: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Structural insights into the human p53 protein as a potential therapeutic target for glioblastoma.

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  • Vidyasri: M.Sc. Microbiology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University).

    • Title: Qualitative and quantitative analysis of plasmid DNA miniprep samples.

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  • ​Vijaya: M.Sc. Microbiology, GITAM University, Visakhapatnam.​

    • Title: Designing specific primers targeting multiple genomic sites of HIV-1 clade-B towards CRISPR/Cas9-based HIV diagnosis.

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  • Vijaykumar: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Pros and cons of targeting the human p53 mutants therapeutically for the treatment of glioblastoma.

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  • Vinaykumar: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Structural insights into the HMGA1 transcription factor for therapeutic intervention in type-2 diabetes.

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  • Vyshnavi: M.Sc. Biotechnology, Maharajah's Postgraduate College, Vijayanagaram (Affl.: Andhra University).

    • Title: Structural insights into the gp120 protein of HIV-1 mutant strains compared to the wild type strain for antibody design.

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  • ​Yamini: M.Sc. Biotechnology, Dantuluri Narayana Raju College, Bhimavaram (Affl.: Andhra University).

    • Title: Dependence of the final product concentration on the number of cycles in polymerase chain reaction.

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  • Yogita: M.Sc. Biochemistry, Sri Padmavati Mahila Visva Vidyalayam, Tirupathi.

    • Title: Structural analysis of K-Ras G12V/D mutants that are clinically seen in cervical cancer patients for drug discovery opportunities.

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